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Abstract: This paper describes the Virtual Laboratory for e-Health system which is currently being developed in the EU IST ViroLab project. The Virtual Laboratory is an environment that enables clinical researchers to prepare and execute computing experiments using a distributed Grid infrastructure, while not requiring in-depth Grid computing technologies knowledge. By virtualizing the hardware, computing infrastructure and databases, the Virtual Laboratory is a user friendly environment, with tailored workflow templates to harness and automate such diverse tasks as data archiving, data integration, data mining and analysis, modeling and simulation.